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Updated: Jan 16, 2026

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在脂质纳米颗粒上形成的蛋白冠状体损害了mRNA货物的传递效率

Elizabeth Voke1, Mariah L Arral2, Henry J Squire1

  • 1Department of Chemical and Biomolecular Engineering, University of California, Berkeley, Berkeley, CA, USA.

Nature communications
|September 30, 2025
PubMed
概括

脂质纳米颗粒 (LNP) 形成蛋白质冠状,影响RNA传递. 这项研究开发了一种质谱法来分析LNP冠状,揭示了影响细胞吸收和基因表达的蛋白质.

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