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Updated: Jan 16, 2026

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors
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通过核逆转录酶抑制剂抑制长间隔的核元素-1,减弱了血管化

Jianshuai Ma1, Dayu He1, Mingxuan Zhang1

  • 1Cardiology Department, the Eighth Affiliated Hospital, Joint Laboratory of Guangdong-Hong Kong-Macao Universities for Nutritional Metabolism and Precise Prevention and Control of Major Chronic Diseases, Sun Yat-sen University, Shenzhen, China.

Signal transduction and targeted therapy
|September 30, 2025
PubMed
概括

长间隔的核元素1 (LINE1) 通过激活cGAS-STING通路驱动血管化. 用核逆转录酶抑制剂 (NRTIs) 抑制LINE1为血管化提供了一个有前途的治疗策略.

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