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Updated: Jan 16, 2026

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
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Published on: December 11, 2016

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开发基因优先分数以利用人类遗传证据预测药物副作用

Áine Duffy1,2,3,4, Robert Chen1,2,3,5, David Stein1,2,3,6

  • 1The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Nature communications
|September 30, 2025
PubMed
概括

我们开发了一种计算工具,即副作用遗传优先分数 (SE-GPS),用于使用人类遗传数据预测药物副作用风险. 这一分数有助于在药物开发的早期确定潜在的安全问题.

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