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使用ELISA确定化合物对免疫检查点复合体形成的抑制性质

Katarzyna Kuncewicz1, Marta Spodzieja2

  • 1Department of Biomedical Chemistry, Faculty of Chemistry, University of Gdańsk, Gdańsk, Poland. katarzyna.kuncewicz@ug.edu.pl.

Methods in molecular biology (Clifton, N.J.)
|September 30, 2025
PubMed
概括

酶相关免疫吸收试验 (ELISA) 可以快速选免疫检查点抑制剂. 这种方法有效地评估化合物的抑制潜力,如,对免疫检查点复杂的形成,如BTLA/HVEM.

关键词:
有竞争力的ELISA免疫检查站是免疫检查站类抑制剂 类抑制剂蛋白质-的相互作用蛋白质与蛋白质的相互作用

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In 1971, Peter Perlman and Eva Engvall developed an Enzyme-linked immunosorbent assay (ELISA or EIA). ELISA differs from western blot in that the assays are conducted in microtiter plates or in vivo rather than on an absorbent membrane.
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