在医疗保健中运行机器辅助翻译
Ivan Lopez1,2, David E Velasquez3, Jonathan H Chen4,5,6,7
1Stanford University School of Medicine, Stanford, CA, USA. ivlopez@stanford.edu.
NPJ digital medicine
|October 1, 2025
概括
大型语言模型 (LLM) 通过提供关键医疗保健材料的及时翻译,可以改善数百万英语水平有限的患者的患者安全. 这项研究为将LLM辅助翻译纳入临床实践提供了一份路线图.
科学领域:
- 医疗信息学 医疗信息学
- 自然语言处理自然语言处理.
- 医疗保健管理的管理
背景情况:
- 超过2500万美国患者的英语水平有限,因未翻译的医疗信息而面临风险.
- 目前的翻译服务往往太慢,损害了患者的安全和护理质量.
- 缺乏实施指南阻碍了在医疗保健中采用先进的翻译技术.
研究的目的:
- 为解决对非英语患者的医疗保健材料及时翻译的关键需求.
- 为整合大型语言模型 (LLM) 机器辅助翻译在医疗保健环境中提供实际实施路线图.
- 引导医疗保健领导者和决策者利用LLM来改善健康公平.
主要方法:
- 利用实施研究综合框架 (CFIR) 确定关键的实施因素.
- 分析了五个CFIR领域的考虑因素:创新,个人,内部环境,实施过程和外部环境.
- 开发了一个整合LLM辅助翻译的战略框架.
主要成果:
- 确定了成功的LLM翻译集成的关键实施因素.
- 概述了针对创新,利益相关者参与,组织准备,流程管理和外部政策的具体考虑.
- 为医疗保健系统采用机器辅助翻译提供了一个结构化的方法.
结论:
- 士学位辅助翻译提供了一个可扩展的解决方案,以弥合医疗保健中的语言差距.
- 系统的,以框架为导向的方法对于有效实施翻译技术至关重要.
- 整合LLM可以显著提高患者安全,减少不同患者群体的健康差异.
更多相关视频
相关概念视频
02:07Improving Translational Accuracy
3.5K
3.5K
02:07Improving Translational Accuracy
14.1K
Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...
14.1K
01:31Translation
17.5K
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Proteins are...
Translation Produces the Building Blocks of Life
Proteins are...
17.5K
01:31Translation
155.4K
Lesson: Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of...
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of...
155.4K
01:29Issues And Trends In Healthcare Delivery System
6.1K
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
6.1K
02:28Leaky Scanning
5.6K
During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA. Marilyn Kozak discovered that the sequence RCCAUGG (where R...
5.6K