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Updated: Jan 16, 2026

Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins
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Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins

Published on: July 8, 2025

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距离-AF改进了AlphaFold2预测的蛋白质结构模型,使用用户指定的距离约束

Yuanyuan Zhang1, Zicong Zhang1, Yuki Kagaya2

  • 1Department of Computer Science, Purdue University, West Lafayette, IN, USA.

Communications biology
|October 1, 2025
PubMed
概括

距离-AF通过整合距离约束来增强蛋白质结构预测,在复杂的目标上显著提高了对AlphaFold2的准确性. 这种计算工具通过完善蛋白质模型来帮助结构生物学和药物发现.

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