帕尔沃病毒:对胎儿贫血和水的保守治疗
Lyndsay Creswell1,2, Pranav Pandya1,2, Daniel Stott1,2
1Fetal Medicine Unit, University College London Hospitals NHS Foundation Trust, London, UK.
Acta obstetricia et gynecologica Scandinavica
|October 1, 2025
概括
在COVID-19后,由于季节性受到干扰,先天性帕尔沃病毒B19感染增加. 本综述审查了诊断,管理和结果,介绍了胎儿贫血和胎儿水症的新保守方法.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 传染性疾病 传染性疾病
背景情况:
- 随着COVID-19大流行社会隔离措施,西北欧洲先天性帕维病毒B19感染的增加.
- 帕尔沃病毒B19胎儿感染可以导致严重的贫血,血小板缩,胎儿水和子宫内死亡.
研究的目的:
- 审查有关先天性帕尔沃病毒B19.9的诊断,管理,围产期结果和神经发育后续的当前文献.
- 介绍2024年疫情期间的第三级胎儿医学中心的经验.
- 突出一种新的保守管理策略,用于帕沃病毒相关的胎儿贫血和胎儿水.
主要方法:
- 对有关帕尔沃病毒B19诊断和管理的现有文献进行系统审查.
- 分析母亲血清学和连续的中脑动脉峰值缩速度超声波监测.
- 关于2024年疫情期间胎儿医学中心经验的回顾性案例审查.
主要成果:
- 宫内输血是胎儿贫血/水的主要治疗方法,但存在重大风险.
- 先天性帕沃病毒B19可以导致严重的胎儿并发症和长期的神经发育问题.
- 高等教育中心的经验证明了保守的管理方法的潜在有效性.
结论:
- 有效管理先天性帕沃病毒B19需要对干预措施进行仔细监测和风险效益评估.
- 保守的管理方法可能为特定的帕尔沃病毒相关胎儿贫血和胎儿水病例提供可行的替代方案.
- 需要进一步的研究来验证新的保守策略和长期结果.
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