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肥胖是导致喘负担的主要原因:来自GBD和NHANES分析的见解
Wenxin Zheng1,2, Xiaoxiao Fan1,2, Jian Guan3
1Basic Medical College, Jiamusi University, Jiamusi, 154007, China.
全球喘负担仍然很高,尤其是儿童和老年人. 肥胖的增加是主要的可修改的风险因素,需要体重管理策略来减少喘的发病率和严重程度.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 全球健康 全球健康
背景情况:
- 喘患病率和死亡率显示出复杂的全球趋势.
- 人口变化显著影响喘负担.
- 肥胖是喘管理中的一个新兴的,关键因素.
研究的目的:
- 分析1990-2021年全球喘负担趋势.
- 确定关键的风险因素,重点关注肥胖的影响.
- 评估区域在减轻喘负担方面的有效性.
主要方法:
- 使用的全球疾病负担 (GBD) 数据 (1990-2021) 用于发病率,死亡率和DALYs.
- 用于时间趋势分析的就业joinpoint回归.
- 进行了分解和边界分析;使用了NHANES数据来研究肥胖与喘的关联.
主要成果:
- 喘仍然很普遍,在2021年有3700万个新病例和2140万个DALY.
- 人口变化 (人口增长,老龄化) 推动了DALY的增加.
- 高BMI是喘DALYs的主要全球风险因素,独立预测喘的发病和进展.
结论:
- 尽管标准化发病率正在下降,但喘仍是全球严重的负担,特别是在年轻和老年人群中.
- 肥胖已成为全球喘的主要可修改风险因素.
- 专注于体重管理的紧急,量身定制的公共卫生战略对于控制喘至关重要.
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