乳制品中耐消化和生物活性含量与膀癌之间的关联:一项病例对照研究
Atiyeh Sadat Hosseini1, Seyyed Mostafa Jalali1, Zainab Shateri2
1Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Journal of health, population, and nutrition
|October 1, 2025
概括
乳制品衍生生物活性 (BPs) 的更高摄入量与膀癌的风险显著降低有关. 这些发现表明BP在膀癌的发展中起着保护作用.
科学领域:
- 营养科学 营养科学
- 在瘤学瘤学.
- 生物化学 生物化学
背景情况:
- 膀癌是全球重要的健康问题.
- 生物活性 (BPs) 是稳定的,可吸收的饮食碎片,具有生理效应.
- 乳制品BP与膀癌风险之间的联系需要进行调查.
研究的目的:
- 研究乳制品衍生生物活性 (BPs) 与膀癌风险之间的关联.
- 为了确定饮食中摄入的BP是否会影响患膀癌的几率.
主要方法:
- 一项基于医院的病例控制研究,涉及103例膀癌病例和200例对照.
- 饮食摄入量使用经过验证的168项食物频率问卷 (FFQ) 进行评估.
- 后勤回归分析用于评估血压摄入量与膀癌几率之间的关联.
主要成果:
- 与第一个三分之一相比,在乳制品BP总摄入量的第二和第三分之一中观察到膀癌的几率明显较低.
- 调整后的赔率比 (OR) 为第二个三分之一的0.285 (95% CI:0.116-0.699) 和第三个三分之一的0.130 (95% CI:0.032-0.527).
- 在其他乳制品衍生和膀癌风险之间也发现了显著的反向关联.
结论:
- 研究结果表明,乳制品生物活性 (BPs) 与膀癌风险之间存在潜在的反向关系.
- 需要进一步的纵向或干预研究来证实这些发现.
- 需要进行更多的研究,以了解乳制品BP的具体作用机制.
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