来自不同群群的肠道微生物群的模式和影响因素
Wanghui Song1, Chuangsi Chen1, Xueqing Du1
1College of Ocean and Earth Sciences, Xiamen University, Xiamen, 361000, Fujian, China.
Animal microbiome
|October 1, 2025
概括
虫肠道微生物群主要是由宿主基因塑造的,混合体比纯种动物表现出更复杂的微生物网络. 疾病和抗生素等环境因素破坏微生物平衡,而益生菌促进稳定性,为水产养殖提供了洞察力.
科学领域:
- 水生微生物学 水生微生物学
- 鱼类免疫学 鱼类免疫学
- 动物遗传学 动物遗传学
背景情况:
- 肠道微生物群在鱼的营养,免疫力和抗病能力方面发挥着至关重要的作用.
- 鱼水产养殖在亚洲具有重要意义,使鱼肠道微生物对行业的发展和保护至关重要.
- 主体微生物群的相互作用是相互的,影响宿主健康和稳定.
研究的目的:
- 分析六种鱼种 (纯种和杂交种) 的核心肠道微生物组成和网络结构.
- 研究宿主遗传与环境因素对毛虫肠道微生物群的影响.
- 评估外部因素 (疾病,抗生素,益生菌,料成分) 对微生物群落结构和稳定性的影响.
主要方法:
- 综合分析了来自不同地区的六种鱼种的936个测序文件.
- 在纯种和杂交之间对肠道微生物群的比较分析.
- 评估外部因素对微生物共生网络和社区结构的影响.
主要成果:
- 主体遗传,而不是环境,主要决定了水产养殖的核心肠道微生物群.
- 与纯种群相比,混合群表现出更复杂,更具竞争力和更稳定的肠道微生物群网络.
- 疾病和抗生素简化了微生物群落,而益生菌增强了多样性和稳定性;植物蛋白等料成分也改变了网络的复杂性.
结论:
- 虫肠道微生物群的组成在很大程度上受到宿主遗传的影响,在纯种和杂交品种中有明显的模式.
- 外部因素显著影响微生物群落结构,突出了水产养殖业需要谨慎管理的需要.
- 了解这些微生物动态是改善群健康和水产养殖战略的关键.
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