在养蜂业中使用抗生素的意外后果:无人机健康作为潜在的脆弱性
Alexis Burks1, Patrick Gallagher2, Kasie Raymann3,4
1Department of Biology, University of North Carolina at Greensboro, Greensboro, USA.
Animal microbiome
|October 1, 2025
概括
在蜜蜂养殖中使用氧基环素 (OTC) 抗生素会对蜜蜂无人机的发育,生存和精子活力产生负面影响. 这种农业化学物质暴露也减少了肠道细菌的多样性,引起了人们对蜂蜜蜂群中雄性生殖健康的担忧.
科学领域:
- 养蜂与蜜蜂健康 养蜂与蜜蜂健康
- 昆虫繁殖生物学 昆虫繁殖生物学
- 农化学毒理学 农化学毒理学
背景情况:
- 蜜蜂殖民地损失与女王品质下降和无人机繁殖性能变化有关.
- 农业化学品,包括抗生素氧基环素 (OTC),被怀疑是导致生殖能力下降的因素.
- OTC是一种内分泌干扰化合物,已知对其他动物的繁殖有影响,但它对无人机的影响未被描述.
研究的目的:
- 为了研究氧基环素 (OTC) 暴露对蜜蜂无人机发育,生存,生育能力以及肠道和生殖组织微生物群的潜在影响.
- 描述无人机肠道微生物群,并评估OTC对这些微生物群落的影响.
主要方法:
- 使用了体外养系统,使幼虫暴露于OTC.
- 在现场相关的度下,OTC口服给成熟的无人机.
- 分析了无人机肠道和生殖组织微生物群的组成和丰富度.
- 进行了体外精子毒性测定.
主要成果:
- 幼虫OTC暴露延迟了无人机的发育,降低了生存率,并导致成人组织中可检测的OTC残留物.
- 在成熟的无人机中,口服OTC暴露显著降低了肠道细菌的丰富性和多样性.
- 与生殖组织相关的微生物群在很大程度上不受OTC暴露的影响.
- 环境相关的OTC度在体外证明对无人机精子具有高度毒性.
结论:
- 暴露于氧基环素 (OTC) 对蜜蜂无人机发育,生存,肠道微生物群和精子活力产生负面影响.
- 在养蜂业中使用OTC可能会导致雄性蜜蜂生殖健康降低.
- 进一步的实地研究至关重要,以了解OTC对无人机健康和微生物的更广泛影响,以实现可持续的蜜蜂养殖.
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