在复发性/耐药性多发性髓瘤患者中,对全人类BCMA向的CAR T细胞疗法zevorcabtagene autoleucel进行II期研究

Wenming Chen1, Chengcheng Fu2, Baijun Fang3

  • 1Department of Hematology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China. 13910107759@163.com.

概括

泽沃卡巴丁基自杀细胞 (zevor-cel) 在复发性/耐药性多发性骨髓瘤患者中显示出92.2%的客观反应率. 这种CAR T细胞疗法显示出深度和持久的反应,具有可管理的安全性.

相关概念视频

Treatment Resistant Cancers02:56

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.7K