从内镜到手术:关于早期食道癌症管理的翻译视角
Ming-Xing Pan1, Li-Na Sun2, Mei-Ling Su3
1Digestive Endoscopy Center, Hongqi Hospital Affiliated to Mudanjiang Medical University, Mudanjiang, China.
Frontiers in medicine
|October 1, 2025
概括
这项研究引入了早期食道癌症管理的综合框架,通过加强内镜和手术协调,提高诊断准确度和减少治疗延迟. 它旨在优化患者的治疗结果和医疗保健效率.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 目前的早期食道癌的治疗因内镜和外科手术方法之间的协调分散而受到影响.
- 这导致诊断延迟和治疗决策不一致,影响患者的治疗结果.
研究的目的:
- 为早期食道癌症管理提供综合性临床框架.
- 通过加强多学科合作,提高诊断准确性,减少治疗延迟,并最大限度地减少治疗差异.
主要方法:
- 协同使用先进的内镜技术 (内镜下粘膜切割,内镜粘膜切除) 与胸部手术干预.
- 实施多模式分期协议和简化72小时的临床途径.
- 利用机器学习进行手术内风险分层,并纳入基于能力的培训和基于价值的报销.
主要成果:
- 诊断准确度提高了大约20%.
- 通过72小时的临床途径和实时的多学科合作,减少了治疗延迟.
- 通过系统性障碍干预措施,目标是减少治疗差异的28.7%.
结论:
- 综合框架提高了诊断准确度,并简化了早期食道癌的护理.
- 这种从顺序性到综合性护理的模式转变显示了改善瘤治疗结果和医疗保健资源利用的潜力.
- 未来的工作包括分子分层和健康经济评估,用于精确瘤学.
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