劳动诱导方法的比较有效性,安全性和成本效益:系统性审查
Shahinaz Abdelgaium Elsamani Mohamed1, Mohamed Hamid El Hassan Hamid2
1Obstetrics and Gynaecology, Royal Surrey County Hospital, Guildford, GBR.
Cureus
|October 1, 2025
概括
口服mizoprostol和福利导管是有效的第一线产业诱导的选择. 组合方法和门诊策略可以优化结果,平衡有效性,安全性和成本效益.
科学领域:
- 产科和妇科 产科和妇科
- 生殖医学 生殖医学
- 基于证据的医学基于证据的医学.
背景情况:
- 产业诱导是一种常见的产科干预,用于满期怀孕.
- 全球使用日益增加,需要最佳策略来平衡有效性,安全性和成本效益.
- 对药理学,机械和联合诱导方法的评估至关重要.
研究的目的:
- 为了比较不同劳动诱导方法的有效性,安全性和成本效益.
- 分析接受选择性或指示性诱导的无双性和多双性妇女的结果.
- 为优化诱导策略提供基于证据的建议.
主要方法:
- 按照PRISMA指南进行系统审查.
- 在PubMed,Scopus,Web of Science和Embase中搜索了RCT (2015-2025年).
- 包括10个RCT (n=8,683) 进行叙事综合和Cochrane RoB 2评估.
主要成果:
- 口服mizoprostol和福利导管在宫成熟和诱导方面显示出可比的有效性和安全性.
- 组合方法缩短了诱导到分娩的间隔,并在24小时内增加了阴道分娩的可能性.
- 门诊Foley导管成熟和41周的诱导证明了成本效益.
结论:
- 口服mizoprostol和福利导管是有效的第一线诱导选择.
- 组合方法和门诊策略可以根据患者因素优化结果.
- 在41周的诱导比预期的管理更具成本效益,特别是对于未婚妇女.
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