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Updated: Jan 16, 2026

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在黎巴嫩使用阳离子交换HPLC方法对选定的商业levothyroxine配方进行了比较pH-溶解特征分析:对可互换性的影响

Malak AlBathish1, Azza Gazy1, Marwa Al Jamal1

  • 1Department of Pharmaceutical Technology, Faculty of Pharmacy, Beirut Arab University, Beirut, Lebanon, bau.edu.lb.

Advances in pharmacological and pharmaceutical sciences
|October 1, 2025
PubMed
概括

通用levothyroxine配方在溶解上表现出显著的差异,影响生物等价性. 这种与辅助剂相关的变化引发了人们对低甲状腺症治疗的代用药的担忧.

关键词:
离子交换 HPLC 处理器进行比较分析.溶解溶解是一种莱沃西素的使用方法狭窄的治疗指数.

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