与卡塔尔男性和女性不孕症相关的因素:一项病例对照研究
Haya Alkuwari1, Mohamed Ibrahim1, Nour Darwish1
1College of Medicine, Qatar University, Doha, Qatar.
Qatar medical journal
|October 1, 2025
概括
在卡塔尔确定了不孕不育的危险因素,包括女性的多囊性卵巢综合征和男性的静脉. 生殖系统疾病显著增加不孕不育的几率,无论是性别还是国籍.
科学领域:
- 生殖健康 生殖健康
- 流行病学 流行病学
- 医学研究 医学研究
背景情况:
- 不孕症是一个日益增长的全球健康挑战.
- 导致卡塔尔不孕症的因素需要进一步调查.
- 这项研究解决了对不孕症原因的局部数据的需求.
研究的目的:
- 确定与卡塔尔不孕症相关的人口,生活方式和医疗因素.
- 为了告知生殖健康保健策略和改善患者的结果.
- 为特定地区提供关于不孕不育的见解.
主要方法:
- 一项病例控制研究,涉及51 542名参与者 (25 771例,25 771对照),年龄在18-49岁之间.
- 这些数据是从2016年至2022年间在卡塔尔的27个初级医疗保健中心收集的.
- 根据年龄,性别和国籍进行1:1匹配;根据性别和国籍进行分层分析.
主要成果:
- 多囊性卵巢综合征 (PCOS) 在女性中显著增加了不孕不育的几率 (OR 4.34-5.54).
- 子宫多与女性不孕症密切相关 (OR 3.18-6.05).
- 静脉 (OR 37.75-39.46) 和勃起功能障碍 (OR 4.54-6.59) 显著增加了男性不孕不育的几率.
结论:
- 生殖疾病和并发症是卡塔尔和非卡塔尔人群中不孕症的关键风险因素.
- 需要进一步研究时间关联和额外的风险因素.
- 这些发现可以指导制定有效的不孕症预防策略.
相关概念视频
Infertility in Males
527
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
527
Spermatogenesis
121.9K
Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male...
121.9K
Infertility in Females
3.7K
Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of...
Endometriosis, a condition characterized by abnormal growth of...
3.7K
Disorders of the Male Reproductive System
4.0K
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
4.0K
Factors Affecting the Risk of Infection
13.3K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
13.3K
Sex-linked Disorders
108.3K
Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.
108.3K


