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Updated: Jan 16, 2026

Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies
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在早期发病的结肠直肠癌中,MAPK和JAK/STAT途径的种族特异分子变化

Cecilia Monge1, Brigette Waldrup2, Francisco G Carranza2

  • 1Center for Cancer Research, National Cancer Institute, Bethesda MD.

medRxiv : the preprint server for health sciences
|October 1, 2025
PubMed
概括

早期结直肠癌 (EOCRC) 在西班牙裔/拉丁裔 (H/L) 患者中显示了与非西班牙裔白人 (NHW) 患者相比增加的MAPK通路变化. 这些MAPK路径变化可能会导致EOCRC差异,并影响H/L群体的生存结果.

关键词:
在JAK/STAT路径中.通过MAPK路径.癌症的差异和差异 癌症的差异早期发作的结直肠癌.遗传突变 基因突变精准医学是一门精准医学.

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