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Updated: Jan 16, 2026

Assays for Validating Histone Acetyltransferase Inhibitors
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层次的小分子抑制 MYST 乙转移酶的

Xuemin Chen1, Alexandra Castroverde1, Minervo Perez1

  • 1Chemical Biology Laboratory, National Cancer Institute, Frederick, Maryland, 21702, United States.

bioRxiv : the preprint server for biology
|October 1, 2025
PubMed
概括

MYST lysine acetyltransferases (KATs) 抑制剂表现出剂量依赖的目标参与和等级效应. 这项研究定义了它们的效力和选择性,为癌症治疗中监测KAT抑制剂活性提供了生物标志物.

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