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Updated: Jan 16, 2026

Optimizing the Genetic Incorporation of Chemical Probes into GPCRs for Photo-crosslinking Mapping and Bioorthogonal Chemistry in Live Mammalian Cells
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基于纳米体的结合物向小分子结合的GPCRs,并表现出逻辑门的信号传递

Shivani Sachdev1, Swarnali Roy1, Ross W Cheloha1

  • 1Laboratory of Bioorganic Chemistry; National Institutes of Diabetes, Digestive, and Kidney Diseases; National Institutes of Health, USA.

bioRxiv : the preprint server for biology
|October 1, 2025
PubMed
概括

新型比托普纳米体-连接体结合物通过准不同的位点来激活G蛋白结合受体 (GPCRs). 这种双重准的方法使得逻辑门受体对激活用于选择性信号和药物发现.

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