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在慢性病毒挑战性感染期间,病毒特异的Th1细胞中,人群内部异质性的稳定特征

Valerie Plajer1,2, Adrián Madrigal-Avilés1,2,3, Maria Dzamukova1,2

  • 1Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Rheumatology and Clinical Immunology, Experimental Immunology and Osteoarthritis Research, 10117 Berlin, Germany.

bioRxiv : the preprint server for biology
|October 1, 2025
PubMed
概括

特定于病毒的CD4+ T辅助1细胞表现出多样化的T-bet表达水平,即使在慢性感染期间也保持这些差异. 这种异质性持续存在,影响了对病毒挑战的免疫反应.

关键词:
CD4 T 细胞是 CD4 的 T 细胞.在T-bet上下注.在 Th1 细胞中.慢性感染 慢性感染疲 疲 疲 疲 疲定量稳定性的定量稳定性

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