在男性良性前列腺增生症的花粉提取物和tapolioside-based补充剂的性安全性和有效性:一个前性观察性研究
Matteo Vittori1, Valerio Iacovelli1, Marco Carilli1
1Urology Unit, San Carlo di Nancy General Hospital - GVM Care and Research, Rome; Minimally Invasive and Robotic Urology Unit, Tor Vergata University of Rome.
概括
这项研究发现,花粉提取物和tapolioside补充剂改善了男性良性前列腺增生 (BPH) 的生活质量和尿功能,而不会对性健康产生负面影响. 该补充剂耐受性良好,为BPH管理提供了潜在的非药理选择.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 营养保健品 营养保健品
- 男人的健康 男人健康
背景情况:
- 良性前列腺增生症 (BPH) 通常会导致下泌尿道症状 (LUTS),影响生活质量和性功能.
- 传统的BPH治疗可能会导致不良的性副作用.
- 食补充剂为管理BPH症状提供了潜在的替代方案.
研究的目的:
- 评估BPH男性中含有花粉提取物和tapolioside的食补充剂的性安全性和临床疗效.
- 评估补充剂对LUTS,生活质量和性功能的影响.
主要方法:
- 一项为期90天的前性,单臂观察性研究,涉及25名因BPH而出现中度LUTS的男性.
- 每天补充花粉提取物和tapolioside.
- 主要终点包括性功能 (IIEF-5),射精功能 (MSHQ-EjD),生活质量 (IPSS-QoL) 和患者总体改善印象 (PGI-I).
- 二级终点包括尿流率 (Qmax) 和LUTS严重程度 (IPSS).
主要成果:
- 性和射精功能保持稳定,没有统计学意义上的恶化.
- 在生活质量 (IPSS-QoL) 和患者满意度 (PGI-I) 中观察到显著改善.
- 尿功能显著改善,Qmax增加和IPSS得分降低.
结论:
- 花粉提取物和tapeolioside补充剂耐受性良好,并改善了BPH男性的生活质量和尿路结果.
- 该补充剂不会影响性或射精功能.
- 这凸显了其作为BPH管理的非药理学辅助的潜力,特别是对于担心性副作用的患者.
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