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一个聚合诱导的排放活性基光探头,用于高度选择性和灵敏的检测Hg (II) 离子及其多领域应用

Shiyi Xiong¹, Xinlin Cao¹, Mengying Jia¹

¹Precise Synthesis and Function Development Key Laboratory of Sichuan Province, College of Chemistry and Chemical Engineering, China West Normal University, Nanchong, China.

Luminescence : the journal of biological and chemical luminescence

|October 1, 2025

概括

一个新的基于的光探针可以选择性地检测高灵敏度的离子 (Hg2+). 这种探测器可以实时监测生物样本和水,提供低成本,智能手机兼容的检测方法.

科学领域:

化学传感器化学传感器
生物医学工程生物医学工程
材料科学材料科学材料科学

背景情况:

离子 (Hg2+) 构成重大环境和健康风险.
开发用于Hg2+检测的选择性和敏感探头至关重要.
聚合诱导排放 (AIE) 探头在灵敏度和信号噪声比方面具有优势.

研究的目的:

设计和合成一种基于AIE活性的新型光探针 (L),用于选择性检测Hg2+.
为了评估探测器在各种条件和现实世界样本中的性能.
探索探测器在生物成像和逻辑门模拟方面的潜在应用.

主要方法:

合理设计和合成四乙烯 (TPE) 衍生物修饰四 (L) 探针.
用光谱分析 (光) 来确定探头对Hg2+的选择性和灵敏度.
探针在活细胞,斑马鱼幼虫和真实水样中检测Hg2+的应用.
开发测试条和智能手机应用程序用于Hg2+检测.

主要成果:

合成的探测器L表现出良好的水溶性,一个大的斯托克斯转移,和高光量子产量.
探测器L显示Hg2+对其他金属离子的选择性识别,检测极限低 (25.4nM).
在生物系统和环境水样中成功应用探头L用于Hg2+监测.
使用测试条进行定性检测和通过智能手机应用程序进行半定量检测的演示.
模拟INHIBIT分子逻辑门,使用探测器的可逆切换特性.

结论:

新型基于的AIE光探针L对于敏感和选择性的Hg2+检测是有效的.
该探头在生物成像,环境监测和简单的诊断工具方面具有广泛的适用性.
与智能手机技术的整合为Hg2+检测提供了一个具有成本效益和可访问的平台.

关键词:

一个AEE的特点在Hg (II) 离子中.多领域应用的应用.甲是一种甲.光探测器探测器的光.

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