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Updated: Jan 16, 2026

Bone Marrow Transplantation Procedures in Mice to Study Clonal Hematopoiesis
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Bone Marrow Transplantation Procedures in Mice to Study Clonal Hematopoiesis

Published on: May 26, 2021

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在9/11的第一响应者中,克隆性血液形成的升高具有与年龄有关的明显模式,并依赖IL1RAP进行克隆扩张

Divij Verma1, Rachel Zeig-Owens2,3,4, David G Goldfarb2,3,4

  • 1Department of Oncology, Blood Cancer Institute, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York.

Cancer discovery
|October 1, 2025
PubMed
概括

暴露于9/11世界贸易中心 (WTC) 尘埃的第一响应者具有更高的克隆性血液形成 (CH) 突变率. 这种血液状况显著增加了他们患白血病的风险,IL1RAP被确定为潜在的治疗点.

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Characterizing Mutational Load and Clonal Composition of Human Blood07:58

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