全球淋病发病率:在70个国家进行了系统性审查和元分析
Guilherme Tavares de Arruda1, Jordana Barbosa-Silva2, Patricia Driusso3
1Study Group on Chronic Pain (NEDoC), Laboratory of Research on Electrophysical Agents (LAREF), Physical Therapy Department, Universidade Federal de São Carlos (UFSCar), São Carlos, SP, Brazil.
经期疼痛,或经期障碍,在全球范围内影响超过71%,其中初级经期障碍 (PD) 为73%,二级经期障碍 (SD) 为35%. 这突显出全球健康负担很大,需要医疗保健提供者和公共卫生组织的注意.
科学领域:
- 生殖健康 生殖健康
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 阴经痛,以子宫疼痛为特征,被归类为初级 (PD) 或二级 (SD).
- 以前的患病率估计受到人口重点和语言限制的限制.
- 需要对PD和SD患病率进行全面的全球评估.
研究的目的:
- 估计全球患有异常更年症的患病率,包括初级 (PD) 和二级 (SD) 类型.
- 通过子组分析,识别流行率估计中异质性的潜在来源.
- 评估证据的确定性,以确定全球性经期障碍发病率.
主要方法:
- 2000年至2024年间发表的336项研究的系统综述和元分析.
- 搜索了6个数据库,没有语言限制.
- 使用乔安娜·布里格斯研究所工具评估偏见风险,使用GRADE评估证据确定性.
主要成果:
- 综合的全球患病率为71.3% (95%CI为68.7%-73.8%).
- 初级失经症 (PD) 的患病率为73% (95% CI 68%-78%),而二次失经症 (SD) 的患病率为35% (95% CI 19%-56%).
- 在中美洲 (89.6%),斯里兰卡 (97.7%),成年人 (73.3%) 和大学 (78.4%) 观察到的患病率最高.
结论:
- 淋病症是一个重大的全球健康负担,影响着全世界很大一部分女性.
- 在子组分析中发现了高异质性 (I2 = 99.5%-100%) 和非常低的证据确定性.
- 需要卫生保健提供者和公共卫生组织的紧急关注,以解决月经疼痛的全球影响.
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