更年期和炎症性肠病:系统性审查
Tanvi Kale1, Linda Yoo1, Ellie Kroeger1
1Biobehavioral Nursing and Health Informatics, School of Nursing, University of Washington, Seattle, Washington, United States.
Inflammatory bowel diseases
|October 1, 2025
概括
更年期会影响患有炎症性肠病 (IBD) 的女性,往往导致更年期更早和明显的症状. 需要进一步的研究来开发针对IBD和更年期症状管理的有针对性的干预措施.
科学领域:
- 胃肠病学 胃肠病学
- 妇女健康 妇女健康
- 生殖内分泌学 生殖内分泌学
背景情况:
- 关于更年期对炎症性肠病 (IBD) 症状严重程度和进展的影响的研究有限.
- 更年期涉及卵巢功能停止和生殖荷尔蒙下降,显著影响女性的健康.
- 了解这些影响对于同时管理IBD和更年期症状至关重要.
研究的目的:
- 综合目前关于更年期,其过渡和IBD妇女激素治疗 (HT) 影响的证据.
- 检查对疾病活动的影响,IBD症状严重程度和整体疾病进展.
- 确定有关更年期和IBD相互作用的知识差距.
主要方法:
- 根据PRISMA指南进行了系统的文献审查.
- 五个数据库在没有日期限制的情况下进行了搜索,数据提取/偏差风险评估由多个审稿人进行.
- 结果进行了定性合成,以提供全面的概述.
主要成果:
- 患有IBD的女性比健康对照更早经历更年期.
- 虽然大多数IBD患者报告说没有更年期后症状变化,但有些人经历了症状恶化.
- 荷尔蒙疗法 (HT) 在IBD风险方面显示出混合的结果,但可能会降低发作严重程度;IBD的女性报告了更严重的阴部症状.
结论:
- 更年期和IBD之间的关系是研究不足的.
- 对IBD疾病活动和更年期症状的持续调查至关重要.
- 需要量身定制的干预措施来改善IBD妇女一生的健康状况.
更多相关视频
09:11Systematic Scoring Analysis for Intestinal Inflammation in a Murine Dextran Sodium Sulfate-Induced Colitis Model
Published on: February 14, 2021
10.4K
10:37Perturbations of Circulating miRNAs in Irritable Bowel Syndrome Detected Using a Multiplexed High-throughput Gene Expression Platform
Published on: November 30, 2016
8.6K
相关概念视频
01:30Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
604
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
604
01:27Inflammatory Bowel Disease I: Ulcerative Colitis
844
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
844
01:29Inflammatory Bowel Disease IV: Pharmacological Management
427
Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
Pharmacologic...
427
01:30Inflammatory Bowel Disease II: Crohn's Disease
909
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
909
01:17Irritable Bowel Syndrome I: Introduction
879
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
879
01:17Chronic Bowel Disorders: Introduction
721
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
721