在怀孕期间与代谢功能障碍相关的脂肪性肝病
Hannah W Han1, Peter S Marcus2, Tse-Ling Fong3
1Research Associate, Hoag Digestive Health Institute, Hoag Memorial Hospital Presbyterian, Newport Beach, CA; Undergraduate Student, Yale University, New Haven, CT.
孕妇的代谢功能障碍相关的脂肪性肝病 (MASLD) 增加了孕妇和胎儿并发症的风险. 怀孕期间的早期查和干预可以显著改善结果,并预防未来的健康问题.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 产科和妇科 产科和妇科
- 心血管疾病 心血管疾病
背景情况:
- 代谢功能障碍相关的脂肪性肝病 (MASLD) 是美国最常见的肝病,与心血管疾病有关,并与肥胖和胰岛素抵抗等风险因素共享.
- MASLD影响全球大约10%的人口,经常在孕妇中观察到.
- 怀孕为医疗干预提供了一个独特的窗口,这使得识别MASLD风险因素和这一人口群中的并发症至关重要.
研究的目的:
- 强调提高妇产科医生对MASLD的认识的重要性.
- 强调怀孕为诊断MASLD提供了关键的机会.
- 告知医疗保健提供者关于MASLD与妊娠相关并发症的关联.
主要方法:
- 审查肝脏和产科/妇科领域的临床实践指南.
- 在PubMed中使用与MASLD和怀孕相关的关键词进行文献搜索.
- 在孕妇人群中对MASLD进行英语研究的分析.
主要成果:
- MASLD独立地与不良的产科结果有关,包括妊娠糖尿病,高血压和孕前.
- 与MASLD相关的胎儿并发症包括早产和妊娠年龄大的婴儿.
- 饮食,运动和行为干预措施有效地减少了对母亲和新生儿的不良结果.
结论:
- 建议在孕妇患有易患风险因素的孕妇进行MASLD查.
- 干预对于缓解与MASLD相关的妊娠并发症至关重要.
- 建议在怀孕期间推风险分层和管理MASLD,以预防长期肝脏和心血管疾病.
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