针对结石进行微型皮肤利切除术后的急性损伤:预测因素和后续评估在现实生活中
Federica Passarelli1, Ludovico Maria Basadonna1, Fabio Ciamarra1
1Department of Urology, IRCCS Fondazione Ca' Granda, Policlinico di Milano, Milan, Italy.
概括
急性损伤 (AKI) 影响7%的患者经过迷你透皮利切除术 (mPCNL). 预测因素包括更长的手术时间和更高的手术前sCr,AKI在一些患者中持续存在.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 外科手术的结果
背景情况:
- 石病的管理通常涉及皮肤石切除术 (PCNL).
- 迷你透皮瘤切除术 (mPCNL) 是一种最小的侵入性方法来切除结石.
- 急性损伤 (AKI) 是泌尿外科手术后的潜在并发症.
研究的目的:
- 为了确定在接受mPCNL.患者中AKI的流行率.
- 为了确定与mPCNL之后的AKI发展相关的预测因素.
- 评估在mPCNL后发展AKI的患者功能进展和恢复.
主要方法:
- 对569名接受mPCNL.NL治疗的患者进行了回顾性分析.
- 根据KDIGO标准定义的AKI (sCr增加>0.3 mg/dL或≥1.5×基线).
- 多变量和考克斯回归分析用于确定预测因素和恢复因素.
主要成果:
- AKI发生在7.0%的患者中.
- 预测AKI的因素包括更长的手术时间,更高的手术前sCr和早期并发症.
- 患有AKI的患者的并发症率更高.
- 较低的BMI和没有并发症预测了更快的AKI恢复.
结论:
- 在mPCNL之后,AKI是一个显著的并发症.
- 识别和管理风险因素对于改善患者的治疗结果至关重要.
- 对mPCNL中AKI预防和管理策略的进一步研究是合理的.
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