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COVID-19和炎症性肠病 - 需要知道什么
Anne Godat1, Dimitrios Chistoforidis2, Thomas Greuter3
1Division of Gastroenterology and Hepatology, Canton Hospital St. Gallen, St. Gallen, Switzerland.
Current opinion in immunology
|October 1, 2025
概括
用免疫抑制剂治疗的炎症性肠病 (IBD) 患者没有增加COVID-19感染或并发症的风险. 这篇评论考察了COVID-19的情况.
科学领域:
- 胃肠道学和免疫学
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 炎症性肠病 (IBD),包括克罗恩氏病和性结肠炎,是一种慢性胃肠道疾病,在全球范围内日益流行.
- 世界上有数百万人患有IBD,通常需要免疫抑制疗法,这可能会增加对感染的易感性.
- 随着COVID-19大流行,人们担心IBD等慢性疾病患者的风险增加.
研究的目的:
- 审查当前对COVID-19在炎症性肠病患者中的理解.
- 分析COVID-19对IBD患者的影响,考虑疾病过程和与治疗相关的结果.
主要方法:
- 系统审查最近的科学文献.
- 对IBD群体中SARS-CoV-2感染率和结果的证据分析.
- 在COVID-19的背景下对IBD特定不良事件的评估.
主要成果:
- 最近的证据表明,IBD患者与普通人群相比,并没有面临更高的SARS-CoV-2感染风险.
- 包括免疫抑制剂在内的IBD治疗与COVID-19严重程度或并发症的增加无关.
- 在IBD患者中,COVID-19的病程通常与非IBD患者的病程相似.
结论:
- 患有炎症性肠病的患者不存在感染COVID-19或经历严重后果的高风险.
- 目前对IBD的治疗策略在COVID-19感染方面似乎是安全的.
- 应该继续进行进一步的研究,以便在传染病爆发期间监测IBD患者.
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