睡眠特征和发生心血管疾病的轨迹
Jie Guo1, Linda L Magnusson Hanson2, Torbjörn Åkerstedt3
1Department of Nutrition and Health, China Agricultural University, Beijing, China.
Sleep medicine
|October 1, 2025
概括
长期睡眠模式,特别是当与白天症状相结合时,与心血管疾病 (CVD) 风险有关. 随着时间的推移,睡眠时间的变化可能表明心血管疾病的发展,强调需要动态睡眠评估.
科学领域:
- 心脏病学 心脏病学
- 睡眠医学 睡眠医学
- 流行病学 流行病学
背景情况:
- 心血管疾病 (CVD) 风险与睡眠特征有关,但睡眠模式的长期预后价值尚不清楚.
- 以前的研究通常集中在单个时间点或孤立的睡眠方面,限制了对动态睡眠变化的理解.
研究的目的:
- 研究长期睡眠模式的预后价值及其随时间变化对发生心血管疾病的预后价值.
- 为了确定特定的睡眠特征,单独或与白天症状结合,预测心血管结果.
主要方法:
- 利用了来自24223名瑞典职业健康纵向调查 (SLOSH) 参与者的数据,每两年进行跟踪 (2010-2018).
- 通过自我报告评估睡眠特征,通过国家注册链接确定心血管结果.
- 采用Cox的比例危险和混合效应模型来分析睡眠变量,睡眠轨迹和事件心血管疾病之间的关联.
主要成果:
- 夜间失眠或长时间睡眠 (>8小时) 只有当伴有白天症状时,心血管疾病风险就会增加.
- 参与者在基线时睡眠时间长,但患有心血管疾病的人,随着时间的推移,睡眠时间逐渐增加.
- 没有心血管疾病的长时间睡眠者表现出稳定或下降的睡眠时间模式.
结论:
- 白天症状,特别是睡眠时间延长或增加的症状,可能是心血管疾病前的早期生理变化的信号.
- 评估睡眠模式及其随时间的变化对于预测心血管疾病风险至关重要,超出了静态措施.
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