DNA甲基化调解了转移性子宫内膜透明细胞癌中免疫抑制性瘤微环境

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Updated: Jan 16, 2026

Continuous Fluorescence-Based Endonuclease-Coupled DNA Methylation Assay to Screen for DNA Methyltransferase Inhibitors
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Continuous Fluorescence-Based Endonuclease-Coupled DNA Methylation Assay to Screen for DNA Methyltransferase Inhibitors

Published on: August 5, 2022

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Huiqing Jia1, Yang Chen1, Guofeng Ma2

  • 1Department of Pathology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.

EBioMedicine
|October 1, 2025
PubMed
概括

子宫内膜透明细胞癌 (ECCC) 转移是由表观遗传-免疫轴驱动的,其中DNA甲基化使免疫基因沉默. 这项研究确定了LCK作为治疗点,并制定了ECCC的风险评分.

关键词:
通过DNA甲基化.在 ETS1 规则中.宫内膜的透明细胞癌.免疫抑制瘤微环境 免疫抑制瘤微环境在 LCKCK LCK 中.转移性机制的转移性机制

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