患有SLE的中年和老年人对衰老的看法:单中心横截面研究
Sarah B Lieber1,2, Yvonne Shea3, Sarah P Gottesman3
1Division of Rheumatology, Hospital for Special Surgery, New York City, New York, USA LieberS@hss.edu.
Lupus science & medicine
|October 1, 2025
概括
对衰老的负面自我认知与SLE成年人的生活质量低下有关. 解决这些负面观点可能会改善这个患者群体的与健康有关的生活质量.
科学领域:
- 类风湿病学 类风湿病学
- 老年学是一门学科.
- 心理学 心理学 心理学
背景情况:
- 对衰老的负面自我认知与老年人健康相关生活质量 (HRQoL) 的降低相关.
- 系统性红斑狼 (SLE) 是一种慢性自身免疫性疾病,影响多个器官.
- 了解影响SLE老年患者HRQoL的因素对于有效管理至关重要.
研究的目的:
- 调查积极和负面的自我认知与中年和老年SLE成年人的衰老和结果之间的联系.
- 检查SLE患者对衰老的自我认知与疼痛,抑郁,残疾和虚弱之间的关系.
- 确定干预措施的潜在目标,以改善这一群体的HRQoL.
主要方法:
- 对50岁及以上确诊SLE的成年人进行横截面研究.
- 使用与年龄有关的变化意识 (AARC) 尺度评估老龄化的自我感知.
- 测量结果包括疼痛干扰,抑郁,残疾和虚弱,使用验证的仪器 (PROMIS-29,VLA,FRAIL尺度).
主要成果:
- 对衰老的负面自我认知 (AARC损失) 与增加的疼痛干扰,抑郁和虚弱显著相关.
- 对衰老的积极 (AARC收益) 和消极 (AARC损失) 自我认知都与残疾有关.
- 积极的自我认知与疼痛,抑郁或虚弱之间没有发现显著的关联.
结论:
- 对衰老的负面自我认知是SLE中年和老年人HRQoL下降的独立预测因素.
- 针对负面自我认知衰老的干预措施可能会提高SLE患者的HRQoL.
- 需要进行进一步的研究,以探索将衰老的自我感知与SLE的健康结果联系在一起的机制.
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