扩散性肺性脑膜增白症呈现出Cheerios标志,通过跨支气管肺结核检查来诊断:一个病例报告
Tetsu Hirakawa1, Kiyofumi Shimoji1, Sachiko Shioya2
1Department of Molecular and Internal Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, Japan.
Internal medicine (Tokyo, Japan)
|October 1, 2025
概括
肺结节中的Cheerios标志可能表明扩散性肺脑膜病变. 跨支气管肺冷活检 (TBLC) 对于诊断这种罕见的疾病至关重要,特别是在特纳综合征患者中.
科学领域:
- 肺部病理学 肺部病理学
- 在瘤学瘤学.
- 内分泌学 在内分泌学.
背景情况:
- 奇瑞斯标志,一个环状的肺结节,在CT扫描上具有中央亮度,是一种不常见的发现.
- 扩散性肺性脑膜炎是一种罕见的疾病,其特征是肺部广泛的脑膜状细胞结节.
- 特纳综合征是一种遗传性疾病,可能与各种医学并发症有关.
研究的目的:
- 报告一个患有特纳综合征的患者患有扩散性肺脑膜病变的病例,呈现出Cheerios标志.
- 在这种情况下,评估跨支气管肺冷活检 (TBLC) 的诊断效用.
- 讨论这种罕见疾病的管理和结果.
主要方法:
- 一名48岁的女性患有特纳综合征,出现了扩散的肺结节.
- 胸部计算机断层扫描 (CT) 显示了具有特征的Cheerios标志的结节.
- 经支气管肺活检没有诊断效果.
- 进行了跨支气管肺冷活检 (TBLC),以确定确诊.
主要成果:
- 肺结核肺癌 (TBLC) 揭示了由脑膜状细胞组成的肺结节.
- 免疫组织化学分析显示表皮膜抗原,孕激素受体和CD56.6的阳性.
- 患者被诊断出患有扩散性肺性脑膜炎.
- 停止雌激素和孕激素激素治疗导致疾病稳定,无需进一步治疗.
结论:
- 扩散性肺性脑膜增生症可以表现为Cheerios标志.
- 结核肺癌是一种有价值的诊断工具,用于评估带有Cheerios标志的小肺结节.
- 激素治疗可能在治疗这种疾病方面发挥作用.
相关概念视频
01:24Chronic Obstructive Pulmonary Disease
3.2K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
3.2K
01:17Other Pulmonary Disorders
1.8K
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
1.8K
01:25Pleural Effusion I: Introduction
6.3K
Pleural effusion is an abnormal fluid accumulation in the pleural cavity, a narrow space between the lungs and the chest wall. It is not a disease per se but rather a symptom or indication of an underlying disease. In normal circumstances, this space contains a small amount of fluid (5 to 15 mL), a lubricant facilitating the non-frictional movement of the pleural surfaces.
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
6.3K
01:21Aneurysm II: Clinical Manifestations and Diagnostic Studies
593
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
593
01:24Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features
77
Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
77
01:19Chronic Obstructive Pulmonary Disease IV: Clinical Manifestations
59
Chronic Obstructive Pulmonary Disease, or COPD, is a long-term condition marked by persistent and only partially reversible airflow limitation. It involves two overlapping conditions—chronic bronchitis and emphysema—which often co-appear but differ in dominant symptoms and underlying mechanisms.Chronic Bronchitis FeaturesChronic bronchitis presents with a persistent productive cough and thick, sometimes purulent mucus due to airway inflammation, enlarged mucus glands, and goblet...
59