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扩散权重成像用于评估儿童患者的关节
Michael L Francavilla1, Timothy G Brandon2, Dmitry Khrichenko2
1Whiddon College of Medicine, University of South Alabama, Mobile, AL, USA.
从扩散加权成像 (DWI) 获得的明显扩散系数 (ADC) 值有助于区分正常的成熟信号与儿科圣关节 (SIJ) 炎症. 确定的年龄和骨特定的ADC值提高了年轻人的诊断准确度.
科学领域:
- 放射学 放射学是指放射学
- 儿科成像学 儿科成像学
- 整形外科成像 整形外科成像
背景情况:
- 儿科圣关节 (SIJ) 的成熟信号经常被误诊为炎症.
- 改善的诊断特异性对于对骨不成熟的年轻人进行准确的评估至关重要.
- 扩散权重成像 (DWI) 和明显扩散系数 (ADC) 值显示了提高诊断准确性的潜力.
研究的目的:
- 为SIJ定义规范性的儿科ADC值.
- 建立区分正常与炎症SIJ信号的门.
- 评估儿科SIJ的ADC值的诊断性能.
主要方法:
- 在使用感兴趣区域 (ROI) 的86名年轻人的软骨SIJ中测量了ADC值.
- 分析考虑了年龄组,骨类型 (阴骨/圣骨) 和关节高度 (上部/中部/下部).
- 用接收器操作特征分析 (AUROC) 来推导和验证值.
主要成果:
- 儿科SIJADC值显示了年龄相关的下降,特别是在下阴茎和骨.
- 已确立的ADC值有效地区分了正常与炎症SIJ信号,具有高AUROC值 (在大多数阴茎区域≥0.90).
- 圣器值显示了可接受的表现,尽管在青春期前儿童中较低.
结论:
- 成功确定了SIJ的规范性,年龄和骨特定的儿科ADC值.
- 这些ADC参考值为区分儿童SIJ的正常成熟变化和炎症过程提供了有价值的工具.
- 这些发现提高了儿童SIJ病理学评估的诊断特异性.
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