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微管架构将AMOT稳定性与YAP/TAZ机械传导和Hippo信号连接起来

Giada Vanni1, Anna Citron1, Ambela Suli1

  • 1Department of Molecular Medicine, University of Padova, Padova, Italy.

Nature cell biology
|October 1, 2025
PubMed
概括

微管在机械应力时重组,降解AMOT蛋白质以控制YAP/TAZ活动. 这揭示了细胞机械传导和癌症发展的新机制.

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