鼻腺石病:一个全面的系统综述和元分析: 标题页
Giovanni Salzano1, Veronica Scocca2,3, Umberto Committeri4
1Maxillofacial Surgery Unit, Department of Neurosciences, Reproductive and Odontostomatological Sciences, University Federico II of Naples, University Federico II, Via Pansini 5, Naples, Italy.
概括
内镜辅助切除为腺结石提供了最高的成功率,并发症最小. 需要进行进一步的研究,以优化状石病的管理策略.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 手术创新 在外科创新.
- 医学诊断 医学诊断 医学诊断
背景情况:
- 状石病带来了重大的诊断和治疗挑战.
- 腺的复杂解剖学和接近面部神经使治疗复杂化.
- 有效的管理策略对于保持腺体功能和患者的生活质量至关重要.
研究的目的:
- 系统地审查和对腺结石的治疗方法进行元分析.
- 评估各种干预措施的疗效和安全性,用于状石病.
- 确定状腺结石的最佳管理策略.
主要方法:
- 在遵守PRISMA指南的基础上进行系统审查.
- 在PubMed/MEDLINE,Cochrane图书馆,Scopus和谷歌学者中搜索了符合条件的研究.
- 进行了一项单臂随机效应元分析,对仅内镜,内镜辅助和体外冲击波石 (ESWL) 的结果进行了分析.
- 使用纽卡斯尔-太华尺度评估偏差风险.
主要成果:
- 分析了42项涉及1559名患者的研究.
- 通过内镜辅助切除,获得了最高的无结石率 (93%) 和症状改善 (91%).
- 结合内镜-外部方法显示出更高的并发症率 (24%),但对复杂的石头有效.
- 虽然ESWL的无结石率较低 (58%),但有助于长期控制症状.
- CT导航并没有显著提高清除率 (80%).
- 大多数并发症都是轻微的,没有报告永久的面部神经损伤.
结论:
- 内镜辅助和组合方法是有效的,保护腺的治疗方法.
- ESWL和激光技术可以作为辅助疗法,需要进一步调查.
- 高质量,前性,标准化试验对于建立最佳管理协议至关重要.
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