穿皮冠状动脉干预后心房的发生率和危险因素
1Arrhythmia Center, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, National Center for Cardiovascular Diseases, Beijing, 100037, China.
BMC cardiovascular disorders
|October 1, 2025
概括
新发性心房动 (AF) 影响1.1%的PCI后患者. 使用年龄和以前的PCI的简化模型有效预测AF风险,有助于简化分层.
科学领域:
- 心脏病学 心脏病学
- 临床结果研究研究
背景情况:
- 患有冠状动脉疾病 (CAD) 和心房动 (AF) 的患者面临着不良预后.
- 皮肤穿冠状动脉干预 (PCI) 后新发性AF的发生率和预测因素尚未明确.
- 这项研究旨在描述新发性AF发病率,并确定PCI后的相关风险因素.
研究的目的:
- 通过皮肤冠状动脉干预 (PCI) 后的患者中确定新发动心房动 (AF) 的发生率.
- 确定PCI后新发性AF发展的独立风险因素.
- 评估现有风险评分的预测性能和PCI后AF的简化模型.
主要方法:
- 分析了2013年1月至12月期间接受PCI的8367名患者队列.
- 新发性AF被定义为退院后记录的AF,在指数住院期间不存在.
- 使用考克斯比例危险回归和细灰竞争风险分析来确定风险因素和估计危险比率.
主要成果:
- 在3年随访期间,1.1% (94/8,367) 的患者在3年随访期间发展出新发的AF.
- AF的独立预测因素包括年龄大于56.5岁 (HR 2.97) 和之前的PCI (HR 1.73).
- 仅使用年龄和之前的PCI的简化模型显示,与CHARGE-AF得分相比,预测能力不差.
结论:
- 新发性AF发生在PCI后1.1%的患者中.
- 结合年龄和之前的PCI,简化风险分层模型对预测PCI后的AF有效.
- 这种简化方法可以帮助识别PCI后面临新发AF风险的患者.
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