结合技术增强的家庭运动和针 (TEHEplus) 计划,针对接受免疫治疗的癌症患者的症状:可行性研究
Nada Lukkahatai1, Chitchanok Benjasirisan2, Aomei Shen3
1School of Nursing, Johns Hopkins University, Baltimore, MD, USA. nada.lukkahatai@jhu.edu.
BMC cancer
|October 1, 2025
概括
一个新的技术增强的家庭运动和针 (TEHEplus) 计划是可行的,用于接受免疫治疗的癌症患者. 这项计划在缓解疲劳等症状和改善社会功能方面表现有前途.
科学领域:
- 在瘤学瘤学.
- 综合医学是一个整体的医学.
- 数字健康数字健康
背景情况:
- 癌症免疫治疗可以导致显著的症状负担,影响患者的福祉.
- 为了解决这些症状,开发了一项为期12周的技术增强家庭运动和针 (TEHEplus) 计划.
- 该计划旨在改善疲劳,疼痛,睡眠,焦虑,抑郁,社会功能和身体表现.
研究的目的:
- 开发和测试TEHEplus计划的可行性.
- 评估该计划对癌症患者报告结果和血清生物标志物的影响.
- 评估对技术增强干预措施的坚持和参与.
主要方法:
- 一个两阶段的设计:第一阶段用于程序开发,第二阶段用于试点可行性研究.
- 患有固体瘤的参与者被随机分为四组:常规护理控制,单独使用技术增强的家庭炼 (TEHE),单独使用针 (ACU) 和TEHEplus.
- 通过招生持续时间,干预坚持和每日调查响应率来评估可行性.
主要成果:
- 该TEHEplus计划证明了可行性,参与者实现了50%的炼目标,78%的参与者遵守了针点建议.
- TEHEplus参与者报告说,疲劳 (p=0.02) 和社会功能 (p=0.03) 显著改善.
- 仅仅TEHE的参与者仅在社会功能方面表现出改善 (p=0.03).
结论:
- TEHEplus计划是可行的,并显示出在接受免疫治疗的癌症患者中减轻症状的潜力.
- 初步发现表明,癌症幸存者在症状管理和功能结果方面有好处.
- 需要对更大,更多样化的群体进行进一步的研究,以确认有效性和通用性.
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