周围肌肉强度和肺功能对患有肺结核后肺病患者的功能能力产生负面影响:一项横截面研究
Aline Mendes Leal Rodrigues de Souza1, Davi Luiz Olimpio da Silva2, Matheus Mello da Silva2
1Rehabilitation Sciences Post-Graduation Programme, Augusto Motta University Center (UNISUAM), Rio de Janeiro, Brazil.
概括
结核病后肺部疾病 (PTLD) 损害功能能力,减少外周肌肉强度和肺部扩散,显著影响日常活动. 康复策略对于改善PTLD患者的护理至关重要.
科学领域:
- 肺部病理学 肺部病理学
- 康复医学 康复医学 康复医学
- 临床生理学 临床生理学
背景情况:
- 结核病后的肺病 (PTLD) 是一个越来越令人担忧的问题,即使在成功治疗后,也会导致肺功能和与健康相关的生活质量 (HRQoL) 的降低.
- 在PTLD患者的外周肌肉功能障碍是不太了解,尽管它对身体功能的影响.
研究的目的:
- 为了评估患者在PTLD患者的Glittre日常生活活动测试 (TGlittre) 上的表现.
- 评估TGlittre性能,外围肌肉功能,肺功能和HRQoL之间的关联.
主要方法:
- 一项涉及47名PTLD患者的横截面研究.
- 评估呼吸肌肉强度,手握强度 (HGS),四头肌肌肉强度 (QMS) 和HRQoL (SF-36).
- 使用TGlittre. 的性能评估.
主要成果:
- 分别在34%和25.5%的参与者中观察到降低的HGS和QMS.
- 螺旋计揭示了阻塞性 (46.8%) 和限制性 (31.9%) 模式,其中42.6%显示DLCO.降低.
- TGlittre完成时间与肺扩散 (DLCO),呼吸肌肉强度,HGS,QMS和HRQoL领域显著相关. DLCO,QMS和HGS解释了39%的TGlittre时间变化.
结论:
- PTLD显著损害了功能能力,这是TGlittre性能证明的.
- 肌肉功能障碍,HRQoL降低和肺功能受损是PTLD的特征.
- 肺扩散受损和外围肌肉力量 (PMS) 减少是功能能力下降的独立预测因素,突出显示需要康复.
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