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大型乳腺手术后的慢性疼痛:回顾性队列研究

Victor Van Lishout¹, Steffen Rex, Steffen Fieuws

¹From the Department of Anaesthesiology, University Hospitals of the KU Leuven (VVL, SR, AT), Department of Cardiovascular Sciences (SR, AT), Department of Public Health and Primary Care, Leuven Biostatistics and Statistical Bioinformatics Centre (L-BioStat), KU Leuven (SF) and Departments of Obstetrics and Gynaecology, University Hospital of the KU Leuven, Leuven, Belgium (SH).

European journal of anaesthesiology

|October 2, 2025

概括

乳腺手术后3个月,慢性疼痛影响32%的患者. 麻醉类型,手术程序和辅助放射治疗等因素影响疼痛的发展和持续性.

科学领域:

在瘤学瘤学.
疼痛医学医学疼痛医学
手术研究的研究.

背景情况:

乳腺手术对于乳腺癌治疗至关重要.
手术后持续的疼痛影响了大量患者群体.
了解慢性疼痛预测因素对于改善患者的治疗结果至关重要.

研究的目的:

为了确定乳腺手术后慢性疼痛的发生率.
为了确定与发展慢性疼痛相关的风险因素.
分析术后和治疗因素对疼痛的影响.

主要方法:

追溯队列研究的设计.
包括首次接受单方面乳腺癌手术的女性.
在手术后3个月和6个月的疼痛评分,止痛药的使用和预测因素的分析.

主要成果:

慢性疼痛发生率在3个月后为32%,在6个月后为39%.
苏芬坦尼尔/普罗波麻醉和哨兵节点活检与较低的疼痛发生率有关.
辅助放射治疗和先前存在的3个月的疼痛强烈预测了6个月的疼痛.

结论:

乳房手术后的慢性疼痛是多因素的.
术后因素和长期治疗方式都会影响疼痛.
对疼痛管理策略的进一步研究是有必要的.

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