作为药物吸附剂的天然与有机化质:实验和分子建模
Jonáš Tokarský1, Pavlína Peikertová2, Klára Výšková3
1Department of Thermal Engineering, Faculty of Materials Science and Technology, VSB-Technical University of Ostrava 17. listopadu 15/2172, Ostrava-Poruba 708 00 Czech Republic.
RSC advances
|October 2, 2025
概括
原始的石,像蒙莫里隆石一样,是有效的水污染物吸附剂,没有危险的化学修饰. 未经修改的斯麦克石的性能优于修改的版本,为水处理提供了一个环保的替代方案.
科学领域:
- 环境科学 环境科学
- 材料科学 材料科学 材料科学
- 化学 化学 化学
背景情况:
- 石通常用四级化合物进行修饰,以吸附水污染物.
- 这些修改引入了对环境有害的物质.
- 原始的石可能为改造的吸附剂提供一种可持续的替代品.
研究的目的:
- 为了评估与修改的原始涂石相比,原始涂石对制药污染物的吸附效率.
- 为了确定化学修饰是否增强了石的吸附能力.
- 评估使用未经修改的石膏石的环境可行性.
主要方法:
- 使用原始 (蒙莫里隆尼特,贝德利特,非特罗尼特) 和修改后的斯麦克提特,研究了安皮西林 (AMP) 和拉莫特里金 (LAM) 的吸附.
- 采用福里埃变换红外光谱学,元素分析,X射线粉末衍射,热重力测量和分子建模.
- 量化吸附效率和特征的吸附机制.
主要成果:
- 原始的石膏获得了50mg/g的吸附效率,超过了修改后的石膏 (几十毫克/g).
- 贝德莱特在原始涂料中显示出这两种药物的吸附率最高.
- 吸附机制有所不同,原始的石膏呈现非单层吸附,而修改后的石膏呈现单层吸附.
结论:
- 化学修饰不会增强,而且往往会降低AMP和LAM的吸附效率.
- 原始的石表现出优越或可比的吸附性能.
- 未经修改的石灰岩是水污染物吸附的可行,环保的替代品.
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