微针传递系统用于疫苗和免疫治疗
Haiyao Jia1,2, Jinyuan Liu1, Mengqian Shi1
1State Key Laboratory of Biopharmaceutical Preparation and Delivery Institute of Process Engineering Chinese Academy of Sciences Beijing China.
Smart molecules : open access
|October 2, 2025
概括
微针 (MNs) 提供了一种最少的侵入性方式来输送疫苗,增强免疫反应和患者的遵守. 本综述涵盖了MN材料,制造和疾病预防和免疫治疗中的应用.
科学领域:
- 生物医学工程 生物医学工程
- 免疫学 免疫学 免疫学
- 药物输送系统 药物输送系统
背景情况:
- 微针 (MNs) 是一种微侵袭技术,用于通过皮肤递送药物和疫苗.
- 与传统方法相比,它们利用皮肤的免疫细胞来增强免疫反应.
- 更多的MN提供了改善的患者服从性和抗原稳定性.
研究的目的:
- 提供针对疫苗和治疗药物的微针技术的全面审查.
- 讨论基于MN的疫苗的材料,制造,结构分类和优化.
- 检查MN传递系统在传染病,癌症免疫疗法和免疫相关疾病中的应用.
主要方法:
- 关于微针技术的科学文献的综述.
- 分析材料,制造技术和MNS的结构分类.
- 对抗原和辅助剂在MN疫苗疗效中的作用的评估.
主要成果:
- 基于MN的疫苗显示出优越的患者服药性,抗原稳定性和免疫性.
- 在预防传染病和推进瘤免疫治疗方面,MNs存在各种应用.
- 多核子代表了各种生物医学应用的有希望的平台.
结论:
- 微针技术在疫苗和治疗交付方面取得了重大进展.
- 多种疗法增强免疫反应和患者的服从性,使它们成为一种有价值的工具.
- 对MN应用的进一步研究有望用于治疗传染病和癌症.
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