重症儿童静脉血栓栓塞的血栓预防和危险因素:一项基于医院的病例对照研究
Chimaobi Ezekiel Ijioma1,2, Nelson Obioma Uzor3, Oladoyin Ogunbayo Jolaoye4
1Pediatrics, Abia State Children's Specialist Hospital, Umuahia, NGA.
Cureus
|October 2, 2025
概括
血栓预防疗法显著降低了重症儿童的静脉血栓栓塞 (VTE) 风险,药物或联合方法是最有效的. 然而,它的使用是低于最佳的,需要改进的协议和选,特别是在资源有限的环境中.
科学领域:
- 儿科重症监护医学 儿科重症监护医学
- 血液学 血液学 血液学
- 血管医学 血管医学
背景情况:
- 在儿科重症监护室 (PICU) 的重症儿童面临高静脉血栓栓塞 (VTE) 风险.
- 在儿科患者中使用血栓预防,特别是在资源有限的环境中,研究不足,应用不一致.
研究的目的:
- 评估血栓预防在重症儿科患者的使用,有效性和临床结果.
- 在这个人群中确定血栓栓塞事件的独立预测因子.
主要方法:
- 一项涉及180名尼日利亚重症儿童 (1个月-18岁) 的病例控制研究.
- 通过病例报告表格,病历和临床观察收集的数据.
- 多变量逻辑回归用于识别VTE预测因子.
主要成果:
- 关键的静脉瘤预测指标:中央静脉导管,不动>48小时,BMI>95百分点.
- 缺乏血栓预防会增加静脉瘤风险 (AOR=3.64).
- 药物治疗和联合预防显著降低了VTE的几率.
结论:
- 血栓预防,特别是药物或组合,是有效的减少儿科VTE.
- 低于最佳的利用强调了基于风险的协议和查的必要性.
- 改进的策略对于儿科重症监护的结果至关重要,特别是在资源有限的地区.
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