癌细胞中的NRF2激活抑制了免疫透到瘤微环境中的免疫透

Huaichun Wen1, Takafumi Suzuki1,2, Anqi Zhang1

  • 1Department of Biochemistry and Molecular Biology, Tohoku Medical Megabank Organization, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai, Japan.

iScience
|October 2, 2025
PubMed
概括

在癌细胞中核红色素因子2相关因子2 (NRF2) 激活抑制免疫细胞透到瘤中. 这一发现揭示了将NRF2与癌症恶性和免疫规避联系起来的机制.

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