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在接受先天性心脏手术的新生儿和早期婴儿中形成血栓
Muneaki Matsubara1,2,3, Alessandra Poppe1,2,3, Thibault Schaeffer1,2,3
1Department of Congenital and Pediatric Heart Surgery, Technical University Munich, German Heart Center, Munich, Germany.
International journal of cardiology. Congenital heart disease
|October 2, 2025
概括
血栓形成发生在接受先天性心脏手术的婴儿中有7.3%,最常发生在三管修复后. 这种并发症延长了住院时间,并与手术前的复苏和特定的手术程序有关.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 心血管外科心血管外科
- 新生儿医学 新生儿医学
背景情况:
- 新生儿和早期婴儿的先天性心脏手术带来了独特的挑战.
- 血栓形成是影响患者结果的重大问题.
- 了解风险因素对于预防和管理至关重要.
研究的目的:
- 评估新生儿和接受先天性心脏手术的早期婴儿中血栓形成的发生率和影响.
- 确定特定的外科手术程序和与血栓形成风险增加相关的患者因素.
主要方法:
- 对2331名新生儿和早期婴儿 (≤90天) 的回顾性分析,这些新生儿和早期婴儿接受了先天性心脏手术,并进行了心肺旁路 (2001-2024年).
- 通过跨胸腔心声扫描和心脏导管检测.
- 统计分析以确定血栓形成的独立风险因素.
主要成果:
- 总共有170名患者 (7.3%) 患有瘤.
- 在三管修复 (28.6%),动脉切换手术,静脉动脉关闭和大动脉门修复后,血栓最常见.
- 上腔静脉是最常见的血栓位置;长时间住院观察到 (27对15天).
- 独立的风险因素包括手术前心肺复苏,三管修复和诺伍德手术.
结论:
- 在这个队列中,血栓形成的发生率为7.3%.
- 上腔静脉缩和长时间住院是重要的发现.
- 手术前的心肺复苏,三膜修复和诺伍德手术是发生血栓事件的高风险指标.
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