细菌细胞外囊泡的全球状况,轨迹和趋势:一个图书识别和可视化分析
Haokai Chen1, Qiyu Xie2, Jiayu Cai3
1Department of Orthopedic Surgery and Orthopedic Research Institution, West China Hospital, Sichuan University, Chengdu, China.
Frontiers in microbiology
|October 2, 2025
概括
细菌细胞外囊泡 (BEVs) 显示出越来越多的研究兴趣,特别是在药物输送和癌症免疫治疗方面. 未来的研究很可能会集中在瘤微环境调节和先进的纳米疗法上.
科学领域:
- 生物技术是生物技术.
- 纳米医学是一种纳米医学.
- 免疫学 免疫学 免疫学
背景情况:
- 细菌细胞外囊泡 (BEVs) 是细菌衍生的纳米粒子,在病原和治疗潜力中发挥作用.
- BEVs被探索为免疫治疗剂,药物输送系统和纳米疫苗.
研究的目的:
- 对细菌细胞外囊泡 (BEVs) 的研究现状和发展趋势进行文献计量分析.
- 确定在BEV领域的关键研究集群,有影响力的贡献者和新兴研究方向.
主要方法:
- 从Web of Science核心收藏中对2,836个出版物的图书统计分析 (截至2024年11月30日).
- 使用R包"Bibliometric"和CiteSpace软件进行数据分析和可视化.
- 分析了作者,国家,机构,期刊,主题类别,关键词和参考文献.
主要成果:
- 从2006年到2024年,出版物产出显示出稳定的上升趋势 (年增长15.01%).
- 美国和中国科学院在生产率方面处于领先地位;郭永是极具影响力的研究人员.
- 关键的研究集群包括外膜囊泡,免疫疗法和益生菌;新兴领域是癌症免疫疗法,瘤微环境和药物输送.
结论:
- 基于BEV的药物输送系统是目前重要的研究重点,具有巨大的潜力.
- 预计未来的研究将集中在瘤免疫疗法和调节瘤免疫微环境上.
- 纳米技术和生物医学的进步使BEV能够应对关键的临床挑战.
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