乙型肝炎C腹腔炎被同时发生的甲素抗性黄金葡萄球菌感染所掩盖,在腹腔皮质突变放置后:一个说明性的案例
Chiemeka David Uwakwe1, Racheed Mani2, Sujith Swarna1
1Department of Neurological Surgery, Stony Brook University Hospital, Stony Brook, New York, United States.
Surgical neurology international
|October 2, 2025
概括
肝炎C病毒 (HCV) 可以引起罕见的脑膜炎,模仿MRSA风炎等细菌感染. 迅速的抗病毒治疗在一个疑似分流感染的患者中缓解了症状,突出了考虑病毒原因的必要性.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 肝病学 肝病学是一种肝病学.
背景情况:
- 型肝炎病毒 (HCV) 影响全球数百万人,具有罕见的神经系统并发症.
- 神经学症状,如脑膜炎,在慢性HCV病例中可能会被忽视.
- 这一案例突出了一个患者最初接受治疗的甲素耐药黄金葡萄球菌 (MRSA) 腹腔炎.
研究的目的:
- 报告一种C型肝炎脑膜炎病例.
- 强调在耐火性中枢神经系统 (CNS) 感染中考虑病毒病因的重要性.
- 讨论诊断挑战和治疗影响.
主要方法:
- 一个34岁的男性的病例报告,有静脉注射药物使用史和心室关节突变.
- 最初呈现的症状是分流感染和阳性MRSACSF培养.
- 诊断工作包括CSF分析,成像和对治疗的反应.
主要成果:
- 患者呈现出恶化的腹腔巨和脑脊髓液异常,尽管服用了抗生素.
- 细菌和真菌培养仍然呈阴性,这表明了另一种病因.
- 在用索福斯布维尔-韦尔帕塔斯维尔治疗HCV的抗病毒疗法后,症状迅速消失.
结论:
- 慢性HCV再激活可以呈现为长期的腹腔炎,特别是在低压腹腔巨.
- 在手术后的抗生素耐药性中枢神经系统感染中,应考虑血清学上隐藏的病毒感染.
- 在HCV患者中,抗病毒疗法可能对无菌性CSF概况有益.
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