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为预测术后与希尔施普朗格相关的肠球炎开发了一个名图

Weijun Zheng¹, Weiming Chen¹, Fei Chen²

¹Department of Pediatric Surgery, Fujian Children's Hospital (Fujian Branch of Shanghai Children's Medical Center), College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.

Frontiers in pediatrics

|October 2, 2025

概括

研究人员确定了手术后与希尔施普朗相关的肠球炎 (HAEC) 的关键风险因素. 开发了一种预测性名谱,用于评估希尔施普朗格病 (HSCR) 患者的HAEC风险.

科学领域:

儿科手术儿科手术
胃肠病学胃肠病学
临床研究临床研究

背景情况:

赫施普隆相关肠道炎 (HAEC) 是赫施普隆病 (HSCR) 手术后的一种严重并发症.
识别风险因素和预测HAEC发病率对于改善患者的治疗结果至关重要.

研究的目的:

分析与术后HAEC相关的风险因素.
开发和验证一种用于预测HSCR患者HAEC的诺姆图.

主要方法:

对204名接受手术的HSCR患者进行了回顾性分析.
单变量和多变量逻辑回归用于识别风险因素.
使用ROC曲线,校准图表和DCA曲线构建和验证名图.

主要成果:

手术后的HAEC发生在25.9%的患者中.
重要的风险因素包括手术前的HAEC,HSCR类型 (长段或全结肠腺凝结症),手术前肠道准备不足,以及解肠道并发症.
诺米图表显示出良好的区分能力 (AUC=0.79),校准和临床实用性.

结论:

一个经过验证的诺姆图可以预测HSCR患者的术后HAEC.
诺米图表作为一个有价值的工具,用于风险评估和早期检测HAEC.

关键词:

希尔施普朗相关的肠球炎孩子们的孩子们的孩子们的孩子们这个名字是名ogramogram.预测预测预测有关风险因素的风险因素.

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