海洋微藻提取物对罗战斗鱼 (Betta splendens) 病原体的抗菌活性
Piyapan Manklinniam1, Saranya Phunpruch1,2, Worakrit Worananthakij1,2
1Department of Biology, School of Science, King Mongkut's Institute of Technology Ladkrabang, Bangkok, Thailand.
Open veterinary journal
|October 2, 2025
概括
海洋微藻提取物表现出强大的抗菌特性,特别是来自Isochrysis galbana的乙醇提取物. 这些天然化合物为管理水产养殖中的细菌感染提供了可持续的替代方案.
科学领域:
- 海洋生物学 海洋生物学
- 微生物学 微生物学
- 自然产品化学 自然产品化学
背景情况:
- 海洋微藻具有抗菌特性,为传统药品提供了替代品.
- 研究这些特性可能会导致针对细菌感染的新治疗方法.
研究的目的:
- 评估来自Chlorella sp.,Isochrysis galbana和Chaetoceros calcitrans的原始提取物的抗菌和抗菌活性.
- 为了确定负责观察到的抗微生物作用的生物活性化合物.
主要方法:
- 使用乙醇和六溶剂提取微藻.
- 通过阿加井扩散和微板方法进行抗菌查.
- 确定最小抑制度 (MIC) 和最小杀菌度 (MBC).
- 使用气体染色学-质谱学 (GC-MS) 的植物化学分析.
主要成果:
- 伊.加尔巴纳的乙醇提取物显示出对B. subtilis,S. aureus,P. aeruginosa和A. veronii的显著抗菌活性.
- 来自I. galbana和C. calcitrans的提取物抑制了M. marinum,对贝塔鱼的健康有益.
- 对A. veronii的MIC值低至25毫克/毫升.
- 在I. galbana提取物中,GC-MS发现了Phthalate,Tetradecanoic酸,Hexadecanoic酸和Phytol.
结论:
- 海洋微藻提取物,特别是I. galbana乙醇提取物,对陆地和水生病原体具有强大的抗菌潜力.
- 来自I. galbana和C. calcitrans的生物活性化合物对治疗贝塔鱼中的A. veronii和M. marinum等细菌感染有希望.
- 海洋微藻是水产养殖中疾病控制的可持续来源.
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