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在天体细胞到神经元重编程过程中,通过一种新的病毒结构来动态调节NeuroD1表达水平

Natalie Mseis-Jackson1, Mei Jiang1, Mehek Sharma2

  • 1Department of Neuroscience & Regenerative Medicine, Medical College of Georgia at Augusta University, Augusta, GA 30912, USA.

Molecular therapy. Nucleic acids
|October 2, 2025
PubMed
概括

这项研究设计了一种用于天体细胞到神经元重编程的新型载体. 它可以动态地减少NeuroD1的表达,增强GABAergic神经元的生成,用于再生医学.

关键词:
MT:寡核酸:治疗方法和应用.这是一个神经D1D1.星球细胞是星球细胞.在 miR-12424 里面.这是一个微型RNA.神经元重编程的神经元重编程

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