对于查2型糖尿病男性的阴性腺体缺陷症的AMS问卷的有效性:一个横截面研究
Jaromir Ozana1,2, Katarina Moravcova1,2, Eliska Sovova1
1Department of Sports Medicine and Cardiovascular Rehabilitation, University Hospital Olomouc, Olomouc, Czech Republic.
概括
老龄男性症状 (AMS) 调查问卷与2型糖尿病男性的丸激素水平的相关性很弱. 糖尿病并发症可能会错误地提高AMS得分,使查阴性腺的情况复杂化.
科学领域:
- 内分泌学 在内分泌学.
- 男人的健康 男人健康
- 糖尿病研究 糖尿病研究
背景情况:
- 双胞胎缺血症在患有2型糖尿病 (T2DM) 的男性中普遍存在.
- 在T2DM患者中诊断阴性腺症是具有挑战性的,因为糖尿病并发症的症状重叠.
- 衰老男性症状 (AMS) 调查问卷用于查T2DM下性腺症的有效性是不确定的.
研究的目的:
- 评估T2DM男性的AMS得分和血清丸激素水平之间的相关性.
- 评估AMS问卷在各种切线点的诊断准确性.
- 调查糖尿病并发症对AMS得分的影响.
主要方法:
- 一项涉及158名患有T2DM的男性的横截面研究.
- 参与者填写了AMS问卷,并测量了早晨的丸激素水平.
- 对伴随性疾病的评估,包括神经病变,腎病变和阻塞性睡眠呼吸暂停.
主要成果:
- 在总AMS得分和水平 (ρ = -0.16,P=0.047) 之间发现了适度的反相关性.
- AMS的物理子尺度主要推动了这种相关性.
- 神经病变和神经病变与更高的AMS性亚尺度得分有关.
- 一个AMS切断≥27显示高灵敏度 (91%),但低特异性 (21%) 的<12nmol/L.
结论:
- 在患有T2DM的男性中,AMS得分与丸激素的相关性较弱.
- 糖尿病并发症可以独立膨胀AMS得分,可能导致误诊.
- 在使用AMS问卷来查T2DM患者的阴性腺症时,建议谨慎使用;可能需要更高的切断值.
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